2012•International journal of pediatricsRequires access
Clinical value of exhaled nitric oxide in childhood asthma
Xinxin Gan
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Abstract
Allergic asthma is a chronic obstructive disease of the airways characterized by airway hyperresponsiveness,inflammation and remodeling.Exhaled nitric oxide (eNO) level is highly correlated with eosinophilic airway inflammation.Since the advantage of noninvasion,convenience,and specificity of eNO measurement,it has been widely used as a biomarker.In this article eNO metabolism and its effects on airway physiology and pathophysiology are described.The usefulness of eNO in asthma diagnosis and management is discussed in detail.
Key words:
Asthma; Exhaled nitric oxide; Asthma diagnosis ; Asthma management