2017Journal of the Korean Neurological AssociationOpen access

Remission after Rituximab Therapy in Refractory Myasthenia Gravis

Jin-Mo Park, Hocheol Lee, Jin‐Sung Park

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Abstract

aMyasthenia gravis (MG) is estimated to be refractory in approximately 10% of patients with generalized MG.A 35-year-old man was diagnosed as generalized MG with thymoma.Despite aggressive immunotherapies, his myasthenic symptoms relapsed five times within one year.We therefore administered rituximab for treating the refractory MG, and this resulted in remission.There are few reports on treating MG with rituximab, but this case suggests that rituximab can be an effective treatment option for refractory MG.

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aMyasthenia gravis (MG) is estimated to be refractory in approximately 10% of patients with generalized MG.A 35-year-old man was diagnosed as generalized MG with thymoma.Despite aggressive immunotherapies, his myasthenic symptoms relapsed five times within one year.We therefore administered rituximab for treating the refractory MG, and this resulted in remission.There are few reports on treating MG with rituximab, but this case suggests that rituximab can be an effective treatment option for refractory MG.

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Available abstract

aMyasthenia gravis (MG) is estimated to be refractory in approximately 10% of patients with generalized MG.A 35-year-old man was diagnosed as generalized MG with thymoma.Despite aggressive immunotherapies, his myasthenic symptoms relapsed five times within one year.We therefore administered rituximab for treating the refractory MG, and this resulted in remission.There are few reports on treating MG with rituximab, but this case suggests that rituximab can be an effective treatment option for refractory MG.

Key concepts: Rituximab, Medicine, Refractory (planetary science), Myasthenia gravis, Thymoma, Refractory period, Complete remission, Internal medicine

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