2013•Вестник Санкт-Петербургского университета. Серия 11. МедицинаRequires access
Клинические особенности периферической полинейропатии при склерозирующей миеломе, осложненной развитием POEMS-синдрома
Яковлев Алексей Александрович, Мельникова Елена Валентиновна, Салогуб Галина Николаевна, Захаров Василий Иванович, Михайлов Анатолий Михайлович, Яковлева Мария Васильевна
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Abstract
Osteosclerotic myeloma is a rare disease which is often accompanied by peripheral polyneuropathy and multiple organ disorders. POEMS is an English abbreviation that stands for the main clinical symptoms: P — polyneuropathy, O — organomegaly, E — endocrinopathy, M — monoclonal gammopathy, Sskin changes. The purpose of this study is to evaluate the features of polyneuropathy with verified POEMS-syndrome. The article presents a detailed report of three clinical cases. The study proposes an algorithm investigation of patients with unspecified polyneuropathy.