Osteitis Fibrosa Cystica of Tibia as Initial Manifestation of Primary Hyperparathyroidism

Background: Primary hyperparathyroidism is disease of excessive secretion of parathyroid hormone.Osteitis fibrosa cystica or brown tumor, complication of primary hyperthyroidism is characterized by fibrotic cystic bony changes.Skeletal manifestations in the form of brown tumors are rare occuring in less than 2% of patients suffering from any form of hyperparathyroidism.Case Report: We report a 40-year-old woman with lytic lesions in tibia, diagnosed as osteitis fibrosa cystica secondary to parathyroid adenoma.Conclusion: Patients with primary hyperparathyroidism are usually asymptomatic and clinical presentation of the lesion in tibia is rarely a first sign of the disease.