2017•RSC AdvancesOpen access

Pharmacokinetics of rosmarinic acid in rats by LC-MS/MS: absolute bioavailability and dose proportionality

Jingxian Wang, Guoyuan Li, Tianqi Rui, Kang An, Guochun Li, Tingming Fu, Junsong Li, Liuqing Di, Baochang Cai

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Abstract

The pharmacokinetic properties of RA were characterized as rapid absorption, middle-speed elimination, poor absolute bioavailability, and lack of dose proportionality.

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The pharmacokinetic properties of RA were characterized as rapid absorption, middle-speed elimination, poor absolute bioavailability, and lack of dose proportionality.

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OpenAlex reports 60 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The pharmacokinetic properties of RA were characterized as rapid absorption, middle-speed elimination, poor absolute bioavailability, and lack of dose proportionality.

Key concepts: Bioavailability, Pharmacokinetics, Rosmarinic acid, Chemistry, Proportionality (law), Pharmacology, Absorption (acoustics), Chromatography

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