Cryo-EM structure of a human spliceosome activated for step 2 of splicing
Karl Bertram, Dmitry E. Agafonov, Wen-Ti Liu, Olexandr Dybkov, Cindy L. Will, Klaus Hartmuth, Henning Urlaub, Berthold Kastner, Holger Stark, Reinhard Lührmann
Abstract
Karl Bertram, Dmitry E. Agafonov, Wen-Ti Liu, Olexandr Dybkov, Cindy L. Will, Klaus Hartmuth, Henning Urlaub, Berthold Kastner, Holger Stark, Reinhard Lührmann
Abstract
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Key concepts: Spliceosome, RNA splicing, Helicase, Intron, Ribonucleoprotein, snRNP, Small nuclear ribonucleoprotein, RNA Helicase A