1980•RePub (Erasmus University Rotterdam)Open access

Role of Teichoic Acid in the Binding of Staphylococcus Aureus to Nasal Epithelial Cells

Raza Aly, Henry R. Shinefield, C. Litz, Howard I. Maïbach

Abstract

The role of teichoic acid in the adherence of Staphylococcus aureus to nasal epithelial cells was investigated. Epithelial cells treated with teichoic acid demonstrated decreased binding of S. aureus. A 71% reduction of adherence was noted with teichoic acid-treated epithelial cells as compared with controls (P less than 0.001). Reduction in adherence of S. aureus was also noted with lipoteichoic acid (obtained from streptococci)-treated epithelial cells. The data provide evidence that teichoic acid mediates the adherence of S. aureus to nasal mucosal cells.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Teichoic acid, Staphylococcus aureus, Lipoteichoic acid, Microbiology, Epithelium, Chemistry, Biology, Bacteria