2016•Journal of Pulmonary & Respiratory MedicineRequires access
Spread through Air Spaces Detected in Frozen Sections of Lung Adenocarcinoma is a Sign of Air Space Invasion: A Case Report
Noriah Othman, Yuko Akazawa, Yuka Kitamura
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Abstract
A 70-year-old non-smoking woman was found to have 23 mm sized lung adenocarcinoma. Intraoperative frozen
sections were performed which confirmed the diagnosis of adenocarcinoma. Surgical material revealed presence
of tumor nests spreading through airspaces (STAS) as far as 9 mm from the edge of the main tumor. Based on the
presence of STAS, resection of the remaining left upper lobe was performed after the first operation, and no residual
tumor or STAS was detected. A retrospective review of the frozen sections showed the presence of STAS. This report
indicates that evaluation of STAS at the time of surgery may help improve the clinical course of a patient undergoing
limited resection.