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2017•Journal of Clinical MicrobiologyOpen access

The Ongoing Genetic Adaptation of Streptococcus pneumoniae

Sandra S. Richter, Daniel M. Musher

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Abstract

ABSTRACT Streptococcus pneumoniae has demonstrated a remarkable ability to adapt during the conjugate vaccine era. The increasing incidence of serotype 35B disease and emergence of a multidrug-resistant clone reported in this issue of the Journal of Clinical Microbiology (L. Olarte et al., J Clin Microbiol 55:724–734, 2017, https://doi.org/10.1128/JCM.01778-16 ) underscore the limitations of pneumococcal vaccines that target the polysaccharide capsule.

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What this paper is about

ABSTRACT Streptococcus pneumoniae has demonstrated a remarkable ability to adapt during the conjugate vaccine era. The increasing incidence of serotype 35B disease and emergence of a multidrug-resistant clone reported in this issue of the Journal of Clinical Microbiology (L. Olarte et al., J Clin Microbiol 55:724–734, 2017, https://doi.org/10.1128/JCM.01778-16 ) underscore the limitations of pneumococcal vaccines that target the polysaccharide capsule.

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Available abstract

ABSTRACT Streptococcus pneumoniae has demonstrated a remarkable ability to adapt during the conjugate vaccine era. The increasing incidence of serotype 35B disease and emergence of a multidrug-resistant clone reported in this issue of the Journal of Clinical Microbiology (L. Olarte et al., J Clin Microbiol 55:724–734, 2017, https://doi.org/10.1128/JCM.01778-16 ) underscore the limitations of pneumococcal vaccines that target the polysaccharide capsule.

Key concepts: Streptococcus pneumoniae, Adaptation (eye), Microbiology, Biology, Antibiotics, Neuroscience

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