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2017•Drug Metabolism and PharmacokineticsRequires access

Reversible and time-dependent inhibition (TDI) of CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 in human hepatocyte suspensions by model inhibitors

J. George Zhang, Thuy Ho, Reena Patel, Sarah K. Trisdale, Tim Creegan, David M. Stresser

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Key concepts: CYP2B6, CYP2C9, CYP2C8, CYP2C19, CYP3A4, CYP1A2, CYP2D6, Pharmacology

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Reversible and time-dependent inhibition (TDI) of CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 in human hepatocyte suspensions by model inhibitors — Research Paper | ScholarLens