Анализ коагулопатий у детей при различных стадиях септического процесса

A total 308 children (from 1 month to 17 years of age) were analyzed with the different stages of sepsis: systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis. The coagulopathy occurred in all patients: the range of disseminated intravascular coagulation (DIC) syndrome was 93,5%, the range of liver coagulopathy and separated thrombocytopenia was 6,5%. The stage and mode of syndrome DIC depends on sepsis stage and children's age. We found SIRS in infants was associated with coagulation variant of laboratory (latent) syndrome DIC. Older children with SIRS revealed the fibrinolytic variant of latent syndrome DIC. All children with sepsis had a coagulation variant of latent syndrome DIC, and consumption coagulopathy occurred more frequent in infants.