Comparison of liquid based cytology results with conventional cytology results in screening cervical cancer

Our objective is to compare and evaluate the liquid based cytology (LBC) results with the conventional cytology (CC) results for cervical cancer. Cross sectional study. The results of 1531 women, applied to our outpatient clinic, for cervical cancer screening between the years 2012- 2015, were evaluated. We have applied liquid based cytology on 958 (62.6%) of the patients, and conventional cytology on 573 (37.4%) of the patients. Unsatisfactory smear results for examination were found to be significantly lower in LBC compared to CC (20.3% vs. 0.4%, p < 0.001). Atypical squamous cells of undetermined significance (ASC-US) and atypical squamous cells, cannot exclude high-grade lesion (ASC-H) detection rates were significantly higher in LBC compared to CC (3% vs. 1.7%, p < 0.001). Between the ages 18 to 35, ASC-US and ASC-H rates were also significantly higher in LBC, when compared to CC (5.2% vs. 1%, p < 0.001). Even though ASC-US and ASC-H rates in patients aged 18 to 35 were higher than other groups, no significant difference was observed. Age was a significant risk factor in cervical epithelial anomalies (p < 0.001). LBC was found to be a better method than CC for obtaining accurate results on cervical epithelial anomalies, in all ages