J. Velcicky, A. Soicke, R. Steiner, H.-G. Schmalz
Abstract
Significance Herein, an efficient and general protocol for the cyanomethylation of aryl halides and triflates is disclosed. A wide range of electron-donating or electron-accepting functional groups is tolerated on the aryl halide and the desired products are obtained in good yields.
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Significance Herein, an efficient and general protocol for the cyanomethylation of aryl halides and triflates is disclosed. A wide range of electron-donating or electron-accepting functional groups is tolerated on the aryl halide and the desired products are obtained in good yields.
Key concepts: Halide, Chemistry, Aryl, Palladium, Catalysis, Combinatorial chemistry, Aryl halide, Organic chemistry