Esthetic failure in fixed partial dentures

Objective:The aim of this literature review was to study the underlying mechanisms of the association between periodontal disease and prostate cancer.Methods: This study was literature review study, pubmed searching was used to find scientific article about association of periodontal disease and prostate cancer.Results: Direct correlation between periodontal disease and prostrate cancer is still unclear.It was hyphotesized that microorganisms involved in chronic periodontitis may directly induce mutations in the tumor-suppresor genes and proto-oncogenes or alter the signalling pathways that in turn stimulates cancer growth.Conclusion: Periodontal disease may associate to prostate cancer by mutation induction in tumor-suppresor genes.