2000Indian Journal of Pharmaceutical SciencesRequires access

Evaluation Of Diuretic Potential Of Jussiaea Suffruticosa Linn. Extract In Rats

T. Murugesan, L Manik, An, Kuru Suresh, Mintu Pal, Basudeb Saha

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Abstract

Methanolic extract of the aerial parts of Jussiaea suffruticosa Linn. (MEJS) was evaluated for its diuretic potential in albino rats. The parameters monitored during the evaluation of diuretic potential are total urine volume, body weight before and after the test, concentration of electrolytes such as sodium (Na+), potassium (K+) and chloride (Cl) in urine. The urine volume of the MEJS- treated rats was two fold higher when compared to control (saline) group. Excretions of electrolytes have also been increased when compared to the control group. The diuretic potential of MEJS was statistically significant and comparable to that of the standard diuretic agent furosemide.

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What this paper is about

Methanolic extract of the aerial parts of Jussiaea suffruticosa Linn. (MEJS) was evaluated for its diuretic potential in albino rats. The parameters monitored during the evaluation of diuretic potential are total urine volume, body weight before and after the test, concentration of electrolytes such as sodium (Na+), potassium (K+) and chloride (Cl) in urine. The urine volume of the MEJS- treated rats was two fold higher when compared to control (saline) group. Excretions of electrolytes have also been increased when compared to the control group. The diuretic potential of MEJS was statistically significant and comparable to that of the standard diuretic agent furosemide.

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Available abstract

Methanolic extract of the aerial parts of Jussiaea suffruticosa Linn. (MEJS) was evaluated for its diuretic potential in albino rats. The parameters monitored during the evaluation of diuretic potential are total urine volume, body weight before and after the test, concentration of electrolytes such as sodium (Na+), potassium (K+) and chloride (Cl) in urine. The urine volume of the MEJS- treated rats was two fold higher when compared to control (saline) group. Excretions of electrolytes have also been increased when compared to the control group. The diuretic potential of MEJS was statistically significant and comparable to that of the standard diuretic agent furosemide.

Key concepts: Diuretic, Furosemide, Potassium, Sodium, Chemistry, Diuresis, Urine, Saline

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