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Metformin vs. Pioglitazone as Initial Treatment for Diabetes

Allan S. Brett

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Abstract

Metformin and the thiazolidinediones (e.g., pioglitazone [Actos] and rosiglitazone [Avandia]) are increasingly popular first-line drugs for type 2 diabetes. In this randomized, double-blind multicenter study from Europe, 1199 patients with type 2 diabetes and inadequate responses to diet alone received either metformin (titrated …

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Metformin and the thiazolidinediones (e.g., pioglitazone [Actos] and rosiglitazone [Avandia]) are increasingly popular first-line drugs for type 2 diabetes. In this randomized, double-blind multicenter study from Europe, 1199 patients with type 2 diabetes and inadequate responses to diet alone received either metformin (titrated …

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Available abstract

Metformin and the thiazolidinediones (e.g., pioglitazone [Actos] and rosiglitazone [Avandia]) are increasingly popular first-line drugs for type 2 diabetes. In this randomized, double-blind multicenter study from Europe, 1199 patients with type 2 diabetes and inadequate responses to diet alone received either metformin (titrated …

Key concepts: Pioglitazone, Metformin, Medicine, Rosiglitazone, Type 2 diabetes, Diabetes mellitus, Internal medicine, First line

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