Safety and efficacy analysis of ultrasound-guided percutaneous transhepatic biliary drainage treatment of malignant obstructive jaundice

Objective: To study the clinical effect and prognosis of percutaneous transhepatic biliary \ndrainage (PTBD) treatment of patients with malignant obstructive jaundice. Methods: A total \nof 112 patients with malignant obstructive jaundice treated in our hospital from April 2009 \nto February 2014 were retrospectively analyzed. All patients were randomly divided into \ncontrol group (42 cases) and observation group (70 cases), control group received drainage of \nlaparotomy and observation group received PTBD intervention. All patients were followed up \nfor 3 to 23 months. Clinical effect, complication and length of stay were observed and counted \nafter two groups received different treatment, and the results were compared and analyzed. \nResults: After two groups received different treatment, serum AIL, AST, TBIL and DBIL \nlevels significantly decreased than before treatment, but serum AIL, AST, TBIL and DBIL \nlevels of observation group were lower than those of control group. The levels of WBC and NE \nof both groups were lower than before treatment, but differences in WBC, NE and PT between \nthe two groups were without statistical significance after treatment. Meanwhile, the incidence \nof adverse reaction and length of stay of observation group were lower than those of control \ngroup, and the differences were statistically significant. Conclusion: Interventional treatment \nof malignant obstructive jaundice can effectively improve the clinical symptoms, lower \nincidence of adverse reactions and shorten the length of stay, which is the preferred method for \nmedically inoperable malignant obstructive jaundice and worth clinical popularization.