2015Unpublished venueRequires access

Neuroleptic Malignant Syndrome and Dantrolene. A Case Report

Gustavo Cruz, Sergio Jaramillo, Beatríz Sánchez-Hernández, Fredy Ariza, Angy Cruz, Fundación Valle de Lili, Cruz Suárez

Open publisher page 0 citations

Abstract

Neuroleptic malignant syndrome is a rare condition; manifestations include severe autonomic dysfunction, hyperthermia and muscle rigidity, among others. This may occur in response to drugs that interact with dopaminergic pathways. Diagnosis of this syndrome is mainly clinical since there is no specific laboratory test for this condition and it has a high mortality rate given its multiorgan involvement. This is a case report of a patient who developed neuroleptic malignant syndrome that was managed with supportive therapy and dantrolene.

About this research paper

What this paper is about

Neuroleptic malignant syndrome is a rare condition; manifestations include severe autonomic dysfunction, hyperthermia and muscle rigidity, among others. This may occur in response to drugs that interact with dopaminergic pathways. Diagnosis of this syndrome is mainly clinical since there is no specific laboratory test for this condition and it has a high mortality rate given its multiorgan involvement. This is a case report of a patient who developed neuroleptic malignant syndrome that was managed with supportive therapy and dantrolene.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Neuroleptic malignant syndrome is a rare condition; manifestations include severe autonomic dysfunction, hyperthermia and muscle rigidity, among others. This may occur in response to drugs that interact with dopaminergic pathways. Diagnosis of this syndrome is mainly clinical since there is no specific laboratory test for this condition and it has a high mortality rate given its multiorgan involvement. This is a case report of a patient who developed neuroleptic malignant syndrome that was managed with supportive therapy and dantrolene.

Key concepts: Neuroleptic malignant syndrome, Dantrolene, Muscle Rigidity, Malignant hyperthermia, Medicine, Rhabdomyolysis, Anesthesia, Dantrolene Sodium

Related papers

Back to paper searchBrowse research topicsOriginal source
Neuroleptic Malignant Syndrome and Dantrolene. A Case Report — Research Paper | ScholarLens