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2016•Journal of Pharmacognosy and PhytochemistryRequires access

Pharmacological Activity of Vinca Alkaloids

Anitha Sri S

Open publisher page 10 citations

Abstract

Vinca alkaloids are a set of drugs obtained from the periwinkle plant. They are naturally extracted from the plant Catharanthus roseus, and have hypoglycemic and cytotoxic effects. These are used to treat diabetes, high blood pressure and are also used as disinfectants. The vinca alkaloids are important as they can fight against cancer. The four major vinca alkaloids having medicinal properties are: Vinblastine (VBL), vinorelbine (VRL), vincristine (VCR) and vindesine (VDS). Vinflunine is a new synthetic vinca alkaloid, which has been approved in Europe for the treatment of second-line transitional cell carcinoma of the urothelium. Vinca alkaloids are the second-most-used class of cancer drugs.

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What this paper is about

Vinca alkaloids are a set of drugs obtained from the periwinkle plant. They are naturally extracted from the plant Catharanthus roseus, and have hypoglycemic and cytotoxic effects. These are used to treat diabetes, high blood pressure and are also used as disinfectants. The vinca alkaloids are important as they can fight against cancer. The four major vinca alkaloids having medicinal properties are: Vinblastine (VBL), vinorelbine (VRL), vincristine (VCR) and vindesine (VDS). Vinflunine is a new synthetic vinca alkaloid, which has been approved in Europe for the treatment of second-line transitional cell carcinoma of the urothelium. Vinca alkaloids are the second-most-used class of cancer drugs.

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OpenAlex reports 10 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Vinca alkaloids are a set of drugs obtained from the periwinkle plant. They are naturally extracted from the plant Catharanthus roseus, and have hypoglycemic and cytotoxic effects. These are used to treat diabetes, high blood pressure and are also used as disinfectants. The vinca alkaloids are important as they can fight against cancer. The four major vinca alkaloids having medicinal properties are: Vinblastine (VBL), vinorelbine (VRL), vincristine (VCR) and vindesine (VDS). Vinflunine is a new synthetic vinca alkaloid, which has been approved in Europe for the treatment of second-line transitional cell carcinoma of the urothelium. Vinca alkaloids are the second-most-used class of cancer drugs.

Key concepts: Vinca, Catharanthus roseus, Vinca alkaloid, Vindesine, Vinblastine, Vinorelbine, Alkaloid, Pharmacology

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