Gastric Mucosa-associated Lymphoid Tissue Lymphoma Based on Outcome of Domestic Treatment

Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is associated with Helicobacter pylori infection.H. pylori eradication can be performed as a primary therapy regardless of H. pylori status.In Korea, six articles were published about low-grade gastric MALT lymphoma with H. pylori.Complete regression rate after H. pylori eradication is reported at 74.5% to 94.4%.Radiotherapy results in favorable clinical long-term outcomes in patients with early-stage gastric MALT lymphoma who fail H. pylori eradication therapy and those who are H. pylori negative.Chemotherapy could be reserved for patients with metastatic or high-grade lymphoma.In gastric MALT lymphoma, patients with polypoid type on initial endoscopy had a higher likelihood of recurrence than those with diffuse infiltration or ulceration types.The depth of invasion, location of lesions, and chromosomal abnormality with t(11;18) together are predictive factors for failure to remission by H. pylori eradication.(