2016•Molecular and Cellular EndocrinologyOpen access

Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism

Koshiro Nishimoto, Minae Koga, Tsugio Seki, Kenji Oki, Elise P. Gómez-Sánchez, Celso E. Gómez-Sánchez, Mitsuhide Naruse, Tomokazu Sakaguchi, Shinya Morita, Takeo Kosaka, Mototsugu Oya, Tadashi Ogishima, Masanori Yasuda, Makoto Suematsu, Yasuaki Kabe, Masao Omura, Tetsuo Nishikawa, Kuniaki Mukai

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Key concepts: Steroid 11-beta-hydroxylase, Aldosterone synthase, Primary aldosteronism, Aldosterone, Zona glomerulosa, Adrenal cortex, Zona fasciculata, Hyperaldosteronism