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2016•RSC AdvancesRequires access

Isolation of multiantennary N-glycans from glycoproteins for hepatocyte specific targeting via the asialoglycoprotein receptor

Dominik Witzigmann, Pascal Detampel, Fabiola Porta, Jörg Huwyler

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Abstract

The asialoglycoprotein receptor (ASGPR) expressed on parenchymal liver cells specifically binds multivalent carbohydrates from desialylated glycoproteins.

About this research paper

What this paper is about

The asialoglycoprotein receptor (ASGPR) expressed on parenchymal liver cells specifically binds multivalent carbohydrates from desialylated glycoproteins.

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OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Method / approach

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Available abstract

The asialoglycoprotein receptor (ASGPR) expressed on parenchymal liver cells specifically binds multivalent carbohydrates from desialylated glycoproteins.

Key concepts: Asialoglycoprotein receptor, Glycoprotein, Glycan, Hepatocyte, Chemistry, Receptor, Biochemistry, Cell biology

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Isolation of multiantennary N-glycans from glycoproteins for hepatocyte specific targeting via the asialoglycoprotein receptor — Research Paper | ScholarLens