1999•Nihon Toseki Igakkai ZasshiOpen access

Urinary .ALPHA.1-microglobulin in renal failure: Possible application for determining the induction to maintenance hemodialysis.

Kiyoshi Imaeda, Masanori Shibata, Hideo Uchiyama, Shinkichi Taniguchí, Kazumasa Usami, Shirou Kawashima

Abstract

尿中α-microglobulinを170名の腎疾患患者で測定し, 腎障害の重症度との相関について調べた. 尿中α1-microglobulinは, 血清creatinine, blood urea nitrogen, creatinine clearanceとよく相関した. 特に血清creatinine, blood urea nitrogenがさほど高くないのにcreatinine clearanceが著しく低下している症例ではcreatinine clearanceが低下していない症例に比し, 尿中α1-microglobulinは明らかに高かった (p<0.01).尿中α1-microglobulinの定量は簡便であり特に腎機能の低下している症例で保存期腎不全患者の経過をみるうえで, 維持透析への導入の判定上有用であろうと考えられた.

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Available abstract

Key concepts: Beta-2 microglobulin, Creatinine, Medicine, Blood urea nitrogen, Renal function, Urinary system, Urology, Urea