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Another Study of Pioglitazone Use and Risk for Bladder Cancer

Paul S. Mueller, FACP. FACP.

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Abstract

Evidence is mixed on whether pioglitazone (Actos), an oral thiazolidinedione drug used for managing type 2 diabetes, is associated with excess risk for bladder cancer. In this retrospective cohort study from four European countries, researchers assessed risk for bladder cancer in 56,000 patients (age, >40) with type 2 diabetes who started treatment with pioglitazone. Participants were matched (based …

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What this paper is about

Evidence is mixed on whether pioglitazone (Actos), an oral thiazolidinedione drug used for managing type 2 diabetes, is associated with excess risk for bladder cancer. In this retrospective cohort study from four European countries, researchers assessed risk for bladder cancer in 56,000 patients (age, >40) with type 2 diabetes who started treatment with pioglitazone. Participants were matched (based …

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Available abstract

Evidence is mixed on whether pioglitazone (Actos), an oral thiazolidinedione drug used for managing type 2 diabetes, is associated with excess risk for bladder cancer. In this retrospective cohort study from four European countries, researchers assessed risk for bladder cancer in 56,000 patients (age, >40) with type 2 diabetes who started treatment with pioglitazone. Participants were matched (based …

Key concepts: Pioglitazone, Thiazolidinedione, Medicine, Bladder cancer, Type 2 diabetes, Internal medicine, Cancer, Retrospective cohort study

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