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2016•Emerging infectious diseasesOpen access

Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome

Antônio Augusto Moura da Sílva, Jucelia Sousa Santos Ganz, Patricia da Silva Sousa, Maria Juliana R. Doriqui, Marizélia Rodrigues Costa Ribeiro, Maria dos Remédios Freitas Carvalho Branco, Rejane Christine de Sousa Queiroz, Maria de Jesus Torres Pacheco, Flávia Regina Vieira da Costa, Francelena de Sousa Silva, Vanda Maria Ferreira Simões, Marcos Antônio Barbosa Pacheco, Fernando Lamy Filho, Zeni Carvalho Lamy, Maria Teresa Seabra Soares de Britto e Alves

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Abstract

We report the early growth and neurologic findings of 48 infants in Brazil diagnosed with probable congenital Zika virus syndrome and followed to age 1-8 months. Most of these infants had microcephaly (86.7%) and craniofacial disproportion (95.8%). The clinical pattern included poor head growth with increasingly negative z-scores, pyramidal/extrapyramidal symptoms, and epilepsy.

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What this paper is about

We report the early growth and neurologic findings of 48 infants in Brazil diagnosed with probable congenital Zika virus syndrome and followed to age 1-8 months. Most of these infants had microcephaly (86.7%) and craniofacial disproportion (95.8%). The clinical pattern included poor head growth with increasingly negative z-scores, pyramidal/extrapyramidal symptoms, and epilepsy.

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Available abstract

We report the early growth and neurologic findings of 48 infants in Brazil diagnosed with probable congenital Zika virus syndrome and followed to age 1-8 months. Most of these infants had microcephaly (86.7%) and craniofacial disproportion (95.8%). The clinical pattern included poor head growth with increasingly negative z-scores, pyramidal/extrapyramidal symptoms, and epilepsy.

Key concepts: Zika virus, Medicine, Pediatrics, Microcephaly, Guillain-Barre syndrome, Virology, Intensive care medicine, Virus

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