1988Medical Entomology and ZoologyOpen access

Isolation and sequential analysis of peptides on the venom sac of Parapolybia indica

Takashi Toki, Tadashi Yasuhara, Terumi Nakajima

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Abstract

New analogs of venom peptides such as waspkinin, mastoparan and chemotactic peptide were isolated from the venom sacs of the paper wasp, Parapolybia indica by reversed phase HPLC. Their amino acid sequences were determined as follows : pGlu-Glx-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-Lys, Ile-Asn-Trp-Lys-Lys-Met-Ala-Ala-Thr-Ala-Leu-Lys-Met-Ile-NH_2,HCO-Ile-Leu-Gly-Leu-Leu-Lys-Gly-Ile-Ser-Ala-Leu-Leu-Ser-NH_2.

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New analogs of venom peptides such as waspkinin, mastoparan and chemotactic peptide were isolated from the venom sacs of the paper wasp, Parapolybia indica by reversed phase HPLC. Their amino acid sequences were determined as follows : pGlu-Glx-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-Lys, Ile-Asn-Trp-Lys-Lys-Met-Ala-Ala-Thr-Ala-Leu-Lys-Met-Ile-NH_2,HCO-Ile-Leu-Gly-Leu-Leu-Lys-Gly-Ile-Ser-Ala-Leu-Leu-Ser-NH_2.

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Available abstract

New analogs of venom peptides such as waspkinin, mastoparan and chemotactic peptide were isolated from the venom sacs of the paper wasp, Parapolybia indica by reversed phase HPLC. Their amino acid sequences were determined as follows : pGlu-Glx-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-Lys, Ile-Asn-Trp-Lys-Lys-Met-Ala-Ala-Thr-Ala-Leu-Lys-Met-Ile-NH_2,HCO-Ile-Leu-Gly-Leu-Leu-Lys-Gly-Ile-Ser-Ala-Leu-Leu-Ser-NH_2.

Key concepts: Venom, Mastoparan, Peptide, Chemistry, Amino acid, Biochemistry, Stereochemistry, Receptor

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