2011Current Pediatric ResearchRequires access

Primary pulmonary hemosiderosis-a rare cuase of Microcytic hypochromic anemia

Pankaj Rathi, Rajiv Aggarwal, Usha Kini, B. Purushottam Rao

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Abstract

Iron deficiency anemia (IDA) is the most common cause of anemia in children. In develop-ing countries, the underlying nutritional deprivation makesIDA the most commonly diag-nosed condition and empirical iron supplementation is more or less a norm. Peripheral blood smear picture of microcytic, hypochromic anemia gives an appropriate lead. How-ever, failure of iron therapy and exclusion of its common causes prompts us to look at other diagnostic possibilities. Idiopathic pulmonary hemosiderosis is one such rare condition. We report a two-year female child with persistent microcytic hypochromic anemia with recur-rent hospitalizations for respiratory symptoms not attributable to anemia. The purpose of this paper is to create awareness about Idiopathic Pulmonary Hemosiderosis as a possible but rare cause of microcytic, hypochromic anemia associated with respiratory distress and to delineate diagnostic difficulties and possible pitfalls.

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What this paper is about

Iron deficiency anemia (IDA) is the most common cause of anemia in children. In develop-ing countries, the underlying nutritional deprivation makesIDA the most commonly diag-nosed condition and empirical iron supplementation is more or less a norm. Peripheral blood smear picture of microcytic, hypochromic anemia gives an appropriate lead. How-ever, failure of iron therapy and exclusion of its common causes prompts us to look at other diagnostic possibilities. Idiopathic pulmonary hemosiderosis is one such rare condition. We report a two-year female child with persistent microcytic hypochromic anemia with recur-rent hospitalizations for respiratory symptoms not attributable to anemia. The purpose of this paper is to create awareness about Idiopathic Pulmonary Hemosiderosis as a possible but rare cause of microcytic, hypochromic anemia associated with respiratory distress and to delineate diagnostic difficulties and possible pitfalls.

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Available abstract

Iron deficiency anemia (IDA) is the most common cause of anemia in children. In develop-ing countries, the underlying nutritional deprivation makesIDA the most commonly diag-nosed condition and empirical iron supplementation is more or less a norm. Peripheral blood smear picture of microcytic, hypochromic anemia gives an appropriate lead. How-ever, failure of iron therapy and exclusion of its common causes prompts us to look at other diagnostic possibilities. Idiopathic pulmonary hemosiderosis is one such rare condition. We report a two-year female child with persistent microcytic hypochromic anemia with recur-rent hospitalizations for respiratory symptoms not attributable to anemia. The purpose of this paper is to create awareness about Idiopathic Pulmonary Hemosiderosis as a possible but rare cause of microcytic, hypochromic anemia associated with respiratory distress and to delineate diagnostic difficulties and possible pitfalls.

Key concepts: Microcytic anemia, Medicine, Hypochromic anemia, Hemosiderosis, Anemia, Pediatrics, Respiratory distress, Internal medicine

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