Biochemical consequences of adrenal phenylethanolamine N-methyltransferase (PNMT) inhibition

The adrenal glands of mammals contain large amounts of catecholamines, the principle one being, in most species, epinephrine. Epinephrine, in turn, is formed from norepinephrine via the transfer of a methyl group from S-adenosylmethionine, a reaction catalyzed by the enzyme phenylethanolamine N-methyltransferase (PNMT). These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.