[Biological multifunctionality of resveratrol and its derivatives].

Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural phytoalexin known for its cardioprotective, neuroprotective, anti-inflammatory, anti-cancer and anti-aging properties. Unfortunately, low bioavailability and rapid degradation to less active metabolites limit the use of this compound in a practical medicine. Therefore, lots of attention is paid to synthetic derivatives of resveratrol whose biological properties have repeatedly been recognized to be more pronounced compared with their natural precursor. This paper presents current state of knowledge on the biological activities of resveratrol and its analogues, focusing on so far recognized mechanisms of action of these compounds and their potential applicability.