2016•Molecular PharmacologyOpen access

Synergistic Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Gating by Two Chemically Distinct Potentiators, Ivacaftor (VX-770) and 5-Nitro-2-(3-Phenylpropylamino) Benzoate

Wen‐Ying Lin, Yoshiro Sohma, Tzyh‐Chang Hwang

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Key concepts: Potentiator, Ivacaftor, Cystic fibrosis transmembrane conductance regulator, Gating, Chemistry, Cystic fibrosis, Conductance, Biophysics

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Synergistic Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Gating by Two Chemically Distinct Potentiators, Ivacaftor (VX-770) and 5-Nitro-2-(3-Phenylpropylamino) Benzoate — Research Paper | ScholarLens