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2008•The Internet Journal of NeurosurgeryRequires access

Paraganglioma of the cauda equina

Kavita Mardi, Ramesh Thakur

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Abstract

Paragangliomas of the cauda equina are rare neuroendocrine tumors. We present a case of nonsecreting paraganglioma of the cauda equina, preoperatively misdiagnosed as neurofiroma. A 42year old lady presented with pain and burning sensation in the lower back. MRI showed an intradural / extra medullary well defined mass at the L4,L5 level. Microscopic examination of the resected tumor revealed paraganglioma. The tumor cells were positive for chromagranin and synaptophysin. Although it is difficult to correctly diagnose paraganglioma preoperatively , especially in the region of cauda equina, it should be included in differential diagnoses.

About this research paper

What this paper is about

Paragangliomas of the cauda equina are rare neuroendocrine tumors. We present a case of nonsecreting paraganglioma of the cauda equina, preoperatively misdiagnosed as neurofiroma. A 42year old lady presented with pain and burning sensation in the lower back. MRI showed an intradural / extra medullary well defined mass at the L4,L5 level. Microscopic examination of the resected tumor revealed paraganglioma. The tumor cells were positive for chromagranin and synaptophysin. Although it is difficult to correctly diagnose paraganglioma preoperatively , especially in the region of cauda equina, it should be included in differential diagnoses.

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Available abstract

Paragangliomas of the cauda equina are rare neuroendocrine tumors. We present a case of nonsecreting paraganglioma of the cauda equina, preoperatively misdiagnosed as neurofiroma. A 42year old lady presented with pain and burning sensation in the lower back. MRI showed an intradural / extra medullary well defined mass at the L4,L5 level. Microscopic examination of the resected tumor revealed paraganglioma. The tumor cells were positive for chromagranin and synaptophysin. Although it is difficult to correctly diagnose paraganglioma preoperatively , especially in the region of cauda equina, it should be included in differential diagnoses.

Key concepts: Paraganglioma, Cauda equina, Medicine, Synaptophysin, Medullary cavity, Differential diagnosis, Radiology, Pathology

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