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1. Artificial Receptor for Influenza Virus

R. T. C. Huang, R. Rott, Hans‐Dieter Klenk

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Abstract

Neuraminidase-treated erythrocytes coated with a variety of neuraminic acid-containing glycoproteins adsorbed influenza virus and neuraminidase-free hemagglutinins, but not purified neuraminidase. The results indicate that neuraminic acid is the binding site on the glycoprotein and that the rest of the molecule does not play a specific role in the reaction.

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Neuraminidase-treated erythrocytes coated with a variety of neuraminic acid-containing glycoproteins adsorbed influenza virus and neuraminidase-free hemagglutinins, but not purified neuraminidase. The results indicate that neuraminic acid is the binding site on the glycoprotein and that the rest of the molecule does not play a specific role in the reaction.

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Available abstract

Neuraminidase-treated erythrocytes coated with a variety of neuraminic acid-containing glycoproteins adsorbed influenza virus and neuraminidase-free hemagglutinins, but not purified neuraminidase. The results indicate that neuraminic acid is the binding site on the glycoprotein and that the rest of the molecule does not play a specific role in the reaction.

Key concepts: Neuraminic acid, Neuraminidase, Glycoprotein, Virus, Virology, Chemistry, Sialic acid, Hemagglutinin (influenza)

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