ScholarLens Back to search
2003•Humana Press eBooksRequires access

PCR for the Detection of Influenza Viruses in Clinical Material

Joanna Ellis, David Brown

Open publisher page 2 citations

Abstract

Influenza viruses are segmented, negative-stranded RNA viruses belonging to the family Orthomyxoviridae . They are classified into influenza A, B, and C on the basis of different epitopes on the nucleoprotein (NP) and matrix proteins (M). Influenza A viruses are further divided into subtypes H1N1, H2N2 and H3N2, based on differences in the hemagglutinin (HA) and neuraminidase (NA) genes. The ability of influenza viruses to undergo antigenic change in HA and NA enables the virus to evade the immune response of the host and to cause repeated infections and epidemic spread. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

About this research paper

What this paper is about

Influenza viruses are segmented, negative-stranded RNA viruses belonging to the family Orthomyxoviridae . They are classified into influenza A, B, and C on the basis of different epitopes on the nucleoprotein (NP) and matrix proteins (M). Influenza A viruses are further divided into subtypes H1N1, H2N2 and H3N2, based on differences in the hemagglutinin (HA) and neuraminidase (NA) genes. The ability of influenza viruses to undergo antigenic change in HA and NA enables the virus to evade the immune response of the host and to cause repeated infections and epidemic spread. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Why it matters

OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Influenza viruses are segmented, negative-stranded RNA viruses belonging to the family Orthomyxoviridae . They are classified into influenza A, B, and C on the basis of different epitopes on the nucleoprotein (NP) and matrix proteins (M). Influenza A viruses are further divided into subtypes H1N1, H2N2 and H3N2, based on differences in the hemagglutinin (HA) and neuraminidase (NA) genes. The ability of influenza viruses to undergo antigenic change in HA and NA enables the virus to evade the immune response of the host and to cause repeated infections and epidemic spread. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Key concepts: Neuraminidase, Nucleoprotein, Virology, Hemagglutinin (influenza), Antigenic drift, H5N1 genetic structure, Viral matrix protein, Virus

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
PCR for the Detection of Influenza Viruses in Clinical Material — Research Paper | ScholarLens