[Treatment of intestinal nematode infections with albendazole. Preliminary results (author's transl)].
P Pène, Vincentelli Jm, G Soula, J Delmont, Rossignol Jf
Abstract
P Pène, Vincentelli Jm, G Soula, J Delmont, Rossignol Jf
Abstract
A randomized double-blind study, in order to evaluate effectiveness and tolerance of albendazole, was carried out in 186 african subjects presenting intestinal nematode infections in Mali and Senegal. The drug, well tolerated, given as a single dose of 0.4 g (adolescents and adults) or 0.2 g (children) is curative in more than 90% for ascariasis. For ancylostomiasis and trichuriasis, the effectiveness is less satisfactory in children, probably due to insufficient dosage in this age group.
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A randomized double-blind study, in order to evaluate effectiveness and tolerance of albendazole, was carried out in 186 african subjects presenting intestinal nematode infections in Mali and Senegal. The drug, well tolerated, given as a single dose of 0.4 g (adolescents and adults) or 0.2 g (children) is curative in more than 90% for ascariasis. For ancylostomiasis and trichuriasis, the effectiveness is less satisfactory in children, probably due to insufficient dosage in this age group.
Key concepts: Albendazole, Ancylostomiasis, Trichuriasis, Ascariasis, Hookworm Infections, Nematode, Anthelmintic, Hookworm infection