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2016•Indian Journal of Veterinary PathologyOpen access

Cytological, histological and immunohistochemical evaluation of canine mammary tumors

C.A. Chavan, Megha Kaore, A.G. Bhandarkar, M. S. Dhakate, N.V. Kurkure

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Abstract

Canine mammary tumor is the most common neoplasm with worldwide distribution. In present study a total of 30 spontaneous canine mammary tumors were evaluated based on cytology, histopathology and immunohistochemistry. Histological classification revealed 66% malignancy. Correlation of cytological and histological diagnosis was found to be 70%. Immunohistochemical staining with estrogen receptor (ER) and progesterone receptor (PR)showed decreased expression with progression of malignancy.

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Canine mammary tumor is the most common neoplasm with worldwide distribution. In present study a total of 30 spontaneous canine mammary tumors were evaluated based on cytology, histopathology and immunohistochemistry. Histological classification revealed 66% malignancy. Correlation of cytological and histological diagnosis was found to be 70%. Immunohistochemical staining with estrogen receptor (ER) and progesterone receptor (PR)showed decreased expression with progression of malignancy.

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Available abstract

Canine mammary tumor is the most common neoplasm with worldwide distribution. In present study a total of 30 spontaneous canine mammary tumors were evaluated based on cytology, histopathology and immunohistochemistry. Histological classification revealed 66% malignancy. Correlation of cytological and histological diagnosis was found to be 70%. Immunohistochemical staining with estrogen receptor (ER) and progesterone receptor (PR)showed decreased expression with progression of malignancy.

Key concepts: Pathology, Immunohistochemistry, Medicine, Mammary gland, Biology, Cancer, Internal medicine, Breast cancer

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