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[A case of eosinophilic granuloma of the lymph nodes].

Eiichiro Hirakawa, Ichiro Yamadori, Tsuyoshi Okino, Taiyo Morikawa, Shinichiro Kobayashi, Masako Ohmori

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Abstract

A case of eosinophilic granuloma of the lymph nodes is reported. Two finger-tip-sized masses were recognized in the left postauricular region in a 4-month-old female. Both masses had distended peripheral sinuses occupied by proliferating cells with nuclear indentation. These foci were accompanied with a central necrosis and eosinophils that had infiltrated into the dermis, and were observed also in the efferent lymph duct. Immunohistochemically these cells were positive for S 100 beta, OKT 4, and OKT 6, and were weakly positive for S 100 alpha. These findings suggest that proliferating cells in the T-zone histiocyte lineage might have been somewhat different in this case from usual cases of eosinophilic granuloma.

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What this paper is about

A case of eosinophilic granuloma of the lymph nodes is reported. Two finger-tip-sized masses were recognized in the left postauricular region in a 4-month-old female. Both masses had distended peripheral sinuses occupied by proliferating cells with nuclear indentation. These foci were accompanied with a central necrosis and eosinophils that had infiltrated into the dermis, and were observed also in the efferent lymph duct. Immunohistochemically these cells were positive for S 100 beta, OKT 4, and OKT 6, and were weakly positive for S 100 alpha. These findings suggest that proliferating cells in the T-zone histiocyte lineage might have been somewhat different in this case from usual cases of eosinophilic granuloma.

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Available abstract

A case of eosinophilic granuloma of the lymph nodes is reported. Two finger-tip-sized masses were recognized in the left postauricular region in a 4-month-old female. Both masses had distended peripheral sinuses occupied by proliferating cells with nuclear indentation. These foci were accompanied with a central necrosis and eosinophils that had infiltrated into the dermis, and were observed also in the efferent lymph duct. Immunohistochemically these cells were positive for S 100 beta, OKT 4, and OKT 6, and were weakly positive for S 100 alpha. These findings suggest that proliferating cells in the T-zone histiocyte lineage might have been somewhat different in this case from usual cases of eosinophilic granuloma.

Key concepts: Lymph, Pathology, Eosinophilic, Eosinophilic granuloma, Histiocyte, Granuloma, Medicine, Dermis

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[A case of eosinophilic granuloma of the lymph nodes]. — Research Paper | ScholarLens