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[Steroid receptors in human pathology. Foreword (author's transl)].

Henri Rochefort

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Abstract

After definition of the steroid receptor concept, the different steps of steroid hormone action in the target cell which precede and succeed to the binding of hormone to its receptor are discussed. The different medical applications of steroid hormone receptors are then briefly reviewed such as the assay of steroid receptors in hormone dependant cancer, the understanding of receptor diseases and of antihormones, action, radio-imaging, radio-receptor assay and specific killing of cancer cells containing high level of receptors with bifunctional agents.

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What this paper is about

After definition of the steroid receptor concept, the different steps of steroid hormone action in the target cell which precede and succeed to the binding of hormone to its receptor are discussed. The different medical applications of steroid hormone receptors are then briefly reviewed such as the assay of steroid receptors in hormone dependant cancer, the understanding of receptor diseases and of antihormones, action, radio-imaging, radio-receptor assay and specific killing of cancer cells containing high level of receptors with bifunctional agents.

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Available abstract

After definition of the steroid receptor concept, the different steps of steroid hormone action in the target cell which precede and succeed to the binding of hormone to its receptor are discussed. The different medical applications of steroid hormone receptors are then briefly reviewed such as the assay of steroid receptors in hormone dependant cancer, the understanding of receptor diseases and of antihormones, action, radio-imaging, radio-receptor assay and specific killing of cancer cells containing high level of receptors with bifunctional agents.

Key concepts: Receptor, Hormone receptor, Steroid hormone receptor, Steroid, Steroid hormone, Hormone, Sex hormone receptor, Cancer research

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