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2016•Journal of Applied Pharmaceutical ScienceOpen access

Triterpenes and sterols from Hoya diversifolia Blume

Nelson M. Panajon, Fernando B. Aurigue, Chien‐Chang Shen, Consolacion Y. Ragasa

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Abstract

Chemical investigation of the dichloromethane extracts of Hoya diversifoliaBlume led to the isolation of βamyrin cinnamate (1), squalene (2), β-sitosterol (3), a mixture of β-amyrin (4a), α-amyrin (4b) and lupeol (4c) in a 4:2:1 ratio and saturated hydrocarbons from the leaves; and 2, taraxerol (5), lupeol cinnamate (6), and a mixture of 3 and stigmasterol (7) in a 2:1 ratio from the stems.The structures of 1-7 were identified by comparison of their NMR data with those reported in the literature.

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Chemical investigation of the dichloromethane extracts of Hoya diversifoliaBlume led to the isolation of βamyrin cinnamate (1), squalene (2), β-sitosterol (3), a mixture of β-amyrin (4a), α-amyrin (4b) and lupeol (4c) in a 4:2:1 ratio and saturated hydrocarbons from the leaves; and 2, taraxerol (5), lupeol cinnamate (6), and a mixture of 3 and stigmasterol (7) in a 2:1 ratio from the stems.The structures of 1-7 were identified by comparison of their NMR data with those reported in the literature.

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Available abstract

Chemical investigation of the dichloromethane extracts of Hoya diversifoliaBlume led to the isolation of βamyrin cinnamate (1), squalene (2), β-sitosterol (3), a mixture of β-amyrin (4a), α-amyrin (4b) and lupeol (4c) in a 4:2:1 ratio and saturated hydrocarbons from the leaves; and 2, taraxerol (5), lupeol cinnamate (6), and a mixture of 3 and stigmasterol (7) in a 2:1 ratio from the stems.The structures of 1-7 were identified by comparison of their NMR data with those reported in the literature.

Key concepts: Terpene, Botany, Traditional medicine, Biology, Chemistry, Stereochemistry, Medicine

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