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2004•Humana Press eBooksRequires access

Duck Hepatitis B Virus Model in the Study of Hepatitis B Virus

Lucyna Cova, Fabien Zoulim

Open publisher page 27 citations

Abstract

Because of the narrow host range of hepatitis B virus (HBV) that infects only humans and chimpanzees, the closely related duck HBV (DHBV) provides a particularly useful model, which plays a pivotal role in study of hepadnavirus life cycle, virus-host interactions, and antiviral strategies (1–3). This chapter describes the use of DHBV-infected Pekin duck as an in vivo model and Chapter 16 describes the DHBV primary hepatocyte culture for in vitro studies.

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What this paper is about

Because of the narrow host range of hepatitis B virus (HBV) that infects only humans and chimpanzees, the closely related duck HBV (DHBV) provides a particularly useful model, which plays a pivotal role in study of hepadnavirus life cycle, virus-host interactions, and antiviral strategies (1–3). This chapter describes the use of DHBV-infected Pekin duck as an in vivo model and Chapter 16 describes the DHBV primary hepatocyte culture for in vitro studies.

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Available abstract

Because of the narrow host range of hepatitis B virus (HBV) that infects only humans and chimpanzees, the closely related duck HBV (DHBV) provides a particularly useful model, which plays a pivotal role in study of hepadnavirus life cycle, virus-host interactions, and antiviral strategies (1–3). This chapter describes the use of DHBV-infected Pekin duck as an in vivo model and Chapter 16 describes the DHBV primary hepatocyte culture for in vitro studies.

Key concepts: Duck hepatitis B virus, Virology, Hepatitis B virus, Virus, Biology, Hepadnaviridae

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