[In vitro antibacterial activity of eight third generation cephalosporins (author's transl)].
Lionel Deforges, J Le Van Thoi, Soussy Cj, J Duval
Abstract
Lionel Deforges, J Le Van Thoi, Soussy Cj, J Duval
Abstract
This work report a study of antibacterial activity of eight third generation cephalosporins : cefotaxime, moxalactam, cefoperazone, cefotiam, ceftazidime, ceftriaxone, cefmenoxime and cefotetan. The essential interest of these antibiotics is their activity against Enterobacteriaceae resistant to cefalothin ; however, five of them are clearly superior ; cefotaxime, moxalactam, cefmenoxime, ceftriaxone and ceftazidime. Ceftazidime is the best against Pseudomonas aeruginosa and moxalactam against the Bacteroides group. Against others bacterial groups, these new cephalosporins are not superior to former products.
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This work report a study of antibacterial activity of eight third generation cephalosporins : cefotaxime, moxalactam, cefoperazone, cefotiam, ceftazidime, ceftriaxone, cefmenoxime and cefotetan. The essential interest of these antibiotics is their activity against Enterobacteriaceae resistant to cefalothin ; however, five of them are clearly superior ; cefotaxime, moxalactam, cefmenoxime, ceftriaxone and ceftazidime. Ceftazidime is the best against Pseudomonas aeruginosa and moxalactam against the Bacteroides group. Against others bacterial groups, these new cephalosporins are not superior to former products.
Key concepts: Moxalactam, Cefotiam, Cefotaxime, Ceftazidime, Cefoperazone, Cephalosporin, Latamoxef, Cefotetan