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Glycosaminoglycans in choroid.

Masayuki Kaneko

Abstract

Glycosaminoglycans (GAGs) purified from bovine choroidal tissues were identified and found to be composed of dermatan sulfate with smaller amounts of hyaluronic acid and heparan sulfate. Although biochemical analysis of unsaturated disaccharides (delta DiS) revealed the existence of delta Di-6S and delta Di-4S, corresponding GAG isomers were not identified as spots on the electrophoresis. Dermatan sulfate purified from the choroid seems to be a hybrid containing chondroitin sulfate C and chondroitin sulfate A.

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Key concepts: Dermatan sulfate, Glycosaminoglycan, Heparan sulfate, Hyaluronic acid, Chondroitin sulfate, Chemistry, Chondroitin, Biochemistry