2001•PubMedRequires access
[Acute toxicity of aversectin C : various routes of administration and dosage forms].
Т. С. Новик, Baru Rv, Riabova Va, Chukina Si, Krugliak Eb, Mosin Va, Driniaev Va
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Abstract
The acute oral, cutaneous, and inhalation toxicity of aversectin C was studied on white unbred rats and mice. The compound was less toxic for rats than for mice, the LD50 for oral administration being 90 and 33 mg/kg, respectively. Aversectin C exhibited a maximum acute toxicity upon the inhalation in rats (LD50 = 40 mg/kg), while a minimum toxicity level was observed for the cutaneous application in rats (1700 mg/kg).