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[The estimation of fibrinogen by kinetic immunonephalometry].

H Coquelin, K Mahdouani, Y Boucaud-Maître, P Hutinel, H Cloppet

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Abstract

A new immunonephelometric micromethod for the estimation of fibrinogen is described. The reaction, linear between 0.30 g/l and 11 g/l requires only 5 microliters of plasma. The precision and sensitivity of the method are satisfactory. Comparisons with the chronometric technique of Clauss and with the Mancini immunodiffusion technique were made.

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What this paper is about

A new immunonephelometric micromethod for the estimation of fibrinogen is described. The reaction, linear between 0.30 g/l and 11 g/l requires only 5 microliters of plasma. The precision and sensitivity of the method are satisfactory. Comparisons with the chronometric technique of Clauss and with the Mancini immunodiffusion technique were made.

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Available abstract

A new immunonephelometric micromethod for the estimation of fibrinogen is described. The reaction, linear between 0.30 g/l and 11 g/l requires only 5 microliters of plasma. The precision and sensitivity of the method are satisfactory. Comparisons with the chronometric technique of Clauss and with the Mancini immunodiffusion technique were made.

Key concepts: Fibrinogen, Radial immunodiffusion, Immunodiffusion, Sensitivity (control systems), Chromatography, Chemistry, Biochemistry, Medicine

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