Ahlem Ben Sassi, T Tabka, Pascal Gauduchon, Patrick Dallemagne, Mahjoub Aouni
Abstract
The cytotoxicity of 30 cyclopentanone derivatives was studied in vitro, in a clonogenic assay using murine leukemia L1210. Results are compared to those obtained with reference medicaments. 17 derivatives exhibit activities against L1210 cells.
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The cytotoxicity of 30 cyclopentanone derivatives was studied in vitro, in a clonogenic assay using murine leukemia L1210. Results are compared to those obtained with reference medicaments. 17 derivatives exhibit activities against L1210 cells.
Key concepts: In vitro, Clonogenic assay, Cyclopentanone, L1210 cells, Cytotoxicity, Chemistry, Cytotoxic T cell, Leukemia