1994•Journal of AOAC InternationalRequires access

Chloramphenicol Extraction from Milk by Using the Diphasic Dialysis Method Followed by Liquid Chromatographic Determination

Javier Bayo, Miguel Ángel Moreno, Javier Prieta, Susana Díaz, Guillermo Súarez, Lucas Domı́nguez

Abstract

An economical, fast, and simple method for the extraction and liquid chromatographic determination of chloramphenicol (CAP) in milk is described. CAP is extracted by using a recently developed membrane-based method named "diphasic dialysis." CAP is detected and quantitated in the organic solvent used in dialysis without additional cleanup steps by reversed-phase liquid chromatography and UV detection (270 nm). The determination limit of CAP in milk was about 5 micrograms/L, although as little as 1 microgram/L could be detected under optimal working conditions.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 12 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Chromatography, Chloramphenicol, Dialysis, Extraction (chemistry), Chemistry, Solvent, Dialysis tubing, Membrane