2016•Clinical Cancer Investigation JournalOpen access

Morphometric assessment of microvessel density in head and neck squamous cell carcinoma using immunomarker CD105 and its correlation with clinicopathological parameters

Padam Parmar, Nisha Marwah, Sanjeev Parshad, Taruna Yadav, Sumiti Gupta, Rajeev D. Sen

Abstract

Background: Blood vessel counts using CD105 staining are more informative marker of prognosis as compared with staining by other endothelial markers. We conducted a study to compare intratumoral (IT) and peritumoral (PT) microvessel density (MVD) in head and neck squamous cell carcinoma (HNSCC) using endothelial marker CD105 and its correlation with lymph node metastasis, histological grading, and other clinicopathological parameters. Materials and Methods: Fifty cases of HNSCC with modified rad

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Available abstract

Key concepts: Medicine, Microvessel, Head and neck, Head and neck squamous-cell carcinoma, Basal cell, Endoglin, Pathology, Head and neck cancer