2014arXiv (Cornell University)Open access

A Complete Review of Controlling the FDR in a Multiple Comparison Problem Framework -- The Benjamini-Hochberg Algorithm

Anish Acharya

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Abstract

This paper is a review of the popular Benjamini Hochberg Method and other related useful methods of Multiple Hypothesis testing. This is written with the purpose of serving a short but complete easy to understand review of the main article with proper background. The paper titled 'Controlling the False Discovery Rate-a practical and powerful Approach to multiple Testing' by benjamini et. al.[1] proposes a new framework of controlling the False Discovery Rate in a Multiple Hypothesis testing problem. It has been claimed that the procedure proposed in the paper results in a substantial gain in power more applicable in case of problems which call for False discovery rate (FDR) control rather than Familywise Error Rate (FWER). The proposed method uses a simple Bonferroni type procedure for FDR control.

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This paper is a review of the popular Benjamini Hochberg Method and other related useful methods of Multiple Hypothesis testing. This is written with the purpose of serving a short but complete easy to understand review of the main article with proper background. The paper titled 'Controlling the False Discovery Rate-a practical and powerful Approach to multiple Testing' by benjamini et. al.[1] proposes a new framework of controlling the False Discovery Rate in a Multiple Hypothesis testing problem. It has been claimed that the procedure proposed in the paper results in a substantial gain in power more applicable in case of problems which call for False discovery rate (FDR) control rather than Familywise Error Rate (FWER). The proposed method uses a simple Bonferroni type procedure for FDR control.

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Available abstract

This paper is a review of the popular Benjamini Hochberg Method and other related useful methods of Multiple Hypothesis testing. This is written with the purpose of serving a short but complete easy to understand review of the main article with proper background. The paper titled 'Controlling the False Discovery Rate-a practical and powerful Approach to multiple Testing' by benjamini et. al.[1] proposes a new framework of controlling the False Discovery Rate in a Multiple Hypothesis testing problem. It has been claimed that the procedure proposed in the paper results in a substantial gain in power more applicable in case of problems which call for False discovery rate (FDR) control rather than Familywise Error Rate (FWER). The proposed method uses a simple Bonferroni type procedure for FDR control.

Key concepts: False discovery rate, Multiple comparisons problem, Bonferroni correction, Computer science, Algorithm, Control (management), Word error rate, Data mining

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