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[Histopathological analysis of gastric polyps: classification and relationship to cancer].

Zhao Gh

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Abstract

34 cases of gastric polyps were investigated histopathologically. Based on Nakamura's classification, hyperplastic polyps were further classified into the following subtypes: the foveolar epithelial type, fundic glandular hyperplastic type and pyloric glandular hyperplastic type, each being described in detail. It was found that atypical hyperplastic foci usually appear in the foveolar epithelial subtype, indicating a close relationship to cancer. This finding suggests that the subclassification of hyperplastic gastric polyp has a higher practical value in clinical application. The article has also presented a histochemical and CEA immunohistochemical comparative study between hyperplastic polyps, adenoma and atypical hyperplasia of the stomach. The malignant transformation of gastric polyps is discussed and the definition of polyp reconsidered.

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What this paper is about

34 cases of gastric polyps were investigated histopathologically. Based on Nakamura's classification, hyperplastic polyps were further classified into the following subtypes: the foveolar epithelial type, fundic glandular hyperplastic type and pyloric glandular hyperplastic type, each being described in detail. It was found that atypical hyperplastic foci usually appear in the foveolar epithelial subtype, indicating a close relationship to cancer. This finding suggests that the subclassification of hyperplastic gastric polyp has a higher practical value in clinical application. The article has also presented a histochemical and CEA immunohistochemical comparative study between hyperplastic polyps, adenoma and atypical hyperplasia of the stomach. The malignant transformation of gastric polyps is discussed and the definition of polyp reconsidered.

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Available abstract

34 cases of gastric polyps were investigated histopathologically. Based on Nakamura's classification, hyperplastic polyps were further classified into the following subtypes: the foveolar epithelial type, fundic glandular hyperplastic type and pyloric glandular hyperplastic type, each being described in detail. It was found that atypical hyperplastic foci usually appear in the foveolar epithelial subtype, indicating a close relationship to cancer. This finding suggests that the subclassification of hyperplastic gastric polyp has a higher practical value in clinical application. The article has also presented a histochemical and CEA immunohistochemical comparative study between hyperplastic polyps, adenoma and atypical hyperplasia of the stomach. The malignant transformation of gastric polyps is discussed and the definition of polyp reconsidered.

Key concepts: Hyperplastic Polyp, Foveolar cell, Gastric Polyp, Pathology, Hyperplasia, Stomach, Cancer, Medicine

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