[Prevention of cardiovascular risk in menopause women: role of ovarian hormones].
Rosano Gm, Filippo Leonardo, Simona Ricci, Serra Gb, Sergio Lorenzo Chierchia
Abstract
Rosano Gm, Filippo Leonardo, Simona Ricci, Serra Gb, Sergio Lorenzo Chierchia
Abstract
Women receiving estrogen replacement therapy after menopause have a reduced risk of cardiovascular and cerebrovascular mortality when compared to untreated controls. Estrogens are thought to protect women primarily through an effect on lipid metabolism. However estrogen-induced increase of HDL-cholesterol and decrease of total and LDL-cholesterol appear to account only in part for the protective effect of ovarian hormones. Direct effects of estrogens on the arterial wall appear to contribute to the over-all cardiovascular benefits.
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Women receiving estrogen replacement therapy after menopause have a reduced risk of cardiovascular and cerebrovascular mortality when compared to untreated controls. Estrogens are thought to protect women primarily through an effect on lipid metabolism. However estrogen-induced increase of HDL-cholesterol and decrease of total and LDL-cholesterol appear to account only in part for the protective effect of ovarian hormones. Direct effects of estrogens on the arterial wall appear to contribute to the over-all cardiovascular benefits.
Key concepts: Menopause, Estrogen, Hormone, Medicine, Internal medicine, Endocrinology, Hormone replacement therapy (female-to-male), Cholesterol