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Treatment of herpes simplex keratitis with idoxuridine and vidarabine: a double-blind study.

Chin Gn

Abstract

A double controlled clinical study comparing idoxuridine (IDU) and vidarabine (ara-A) in the treatment of uncomplicated herpes simplex keratitis was carried out with 10 patients. No statistically significant differences occurred in the healing time between IDU (6.8 days) and ara-A (8.0 days). Two moderately adverse reactions to IDU were observed, but no demonstrable ocular toxicity was noted with ara-A.

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Key concepts: Idoxuridine, Vidarabine, Medicine, Keratitis, Dermatology, Adverse effect, Surgery, Virology